Particle-based simulations reveal two positive feedback loops allow relocation and stabilization of the polarity site during yeast mating.

Many cells adjust the direction of polarized growth or migration in response to external directional cues. The yeast Saccharomyces cerevisiae orient their cell fronts (also called polarity sites) up pheromone gradients in the course of mating. However, the initial polarity site is often not oriented...

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Bibliographic Details
Main Authors: Kaiyun Guan, Erin R Curtis, Daniel J Lew, Timothy C Elston
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-10-01
Series:PLoS Computational Biology
Online Access:https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1011523&type=printable