Macrophages and platelets in liver fibrosis and hepatocellular carcinoma

During fibrosis, (myo)fibroblasts deposit large amounts of extracellular matrix proteins, thereby replacing healthy functional tissue. In liver fibrosis, this leads to the loss of hepatocyte function, portal hypertension, variceal bleeding, and increased susceptibility to infection. At an early stag...

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Bibliografski detalji
Glavni autori: Martina Casari, Dominik Siegl, Carsten Deppermann, Detlef Schuppan
Format: Članak
Jezik:English
Izdano: Frontiers Media S.A. 2023-12-01
Serija:Frontiers in Immunology
Teme:
Online pristup:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1277808/full