Neuroproteomic Analysis after SARS-CoV-2 Infection Reveals Overrepresented Neurodegeneration Pathways and Disrupted Metabolic Pathways

Neuroproteomic Analysis after SARS-CoV-2 Infection Reveals Overrepresented Neurodegeneration Pathways and Disrupted Metabolic Pathways

Besides respiratory illness, SARS-CoV-2, the causative agent of COVID-19, leads to neurological symptoms. The molecular mechanisms leading to neuropathology after SARS-CoV-2 infection are sparsely explored. SARS-CoV-2 enters human cells via different receptors, including ACE-2, TMPRSS2, and TMEM106B...

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Bibliographic Details
Main Authors: Indranil Basak, Rhodri Harfoot, Jennifer E. Palmer, Abhishek Kumar, Miguel E. Quiñones-Mateu, Lucia Schweitzer, Stephanie M. Hughes
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:Biomolecules
Subjects:
NeuroCOVID
COVID-19
SARS-CoV-2
iPSC-derived human neurons and astrocytes
proteomics
mass spectrometry
Online Access:https://www.mdpi.com/2218-273X/13/11/1597

Internet

https://www.mdpi.com/2218-273X/13/11/1597

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