Macrophage cytokine responses to commensal Gram-positive Lactobacillus salivarius strains are TLR2-independent and Myd88-dependent

Abstract The mechanisms through which cells of the host innate immune system distinguish commensal bacteria from pathogens are currently unclear. Toll-like receptors (TLRs) are a class of pattern recognition receptors (PRRs) expressed by host cells which recognize microbe-associated molecular patter...

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Bibliographic Details
Main Authors: Sreeram Udayan, Ludovica F. Buttó, Valerio Rossini, Janaki Velmurugan, Maria Martinez-Lopez, David Sancho, Silvia Melgar, Paul W. O’Toole, Ken Nally
Format: Article
Language:English
Published: Nature Portfolio 2021-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-85347-7