Development of a specific troponin I detection system with enhanced immune sensitivity using a single monoclonal antibody

Using an immunoassay in combination with surface plasmon fluorescence spectroscopy (SPFS), we report the rapid detection of troponin I, a valuable biomarker for diagnosis of myocardial infarction. We discuss the implementation of (i) direct, (ii) sandwich, and (iii) competitive assay formats, based...

Full description

Bibliographic Details
Main Authors: Anıl Bozdogan, Reham F. El-Kased, Vanessa Jungbluth, Wolfgang Knoll, Jakub Dostalek, Amal Kasry
Format: Article
Language:English
Published: The Royal Society 2020-10-01
Series:Royal Society Open Science
Subjects:
Online Access:https://royalsocietypublishing.org/doi/pdf/10.1098/rsos.200871