Early death of ALS-linked CHCHD10-R15L transgenic mice with central nervous system, skeletal muscle, and cardiac pathology

Early death of ALS-linked CHCHD10-R15L transgenic mice with central nervous system, skeletal muscle, and cardiac pathology

Summary: Mutations in coiled-coil-helix-coiled-coil-helix domain containing 10 (CHCHD10) have been identified in patients suffering from various degenerative diseases including mitochondrial myopathy, spinal muscular atrophy Jokela type, frontotemporal dementia, and/or amyotrophic lateral sclerosis...

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Bibliographic Details
Main Authors: Éanna B. Ryan, Jianhua Yan, Nimrod Miller, Sudarshan Dayanidhi, Yongchao C. Ma, Han-Xiang Deng, Teepu Siddique
Format: Article
Language:English
Published: Elsevier 2021-02-01
Series:iScience
Subjects:
Molecular Physiology
Molecular Biology
Neuroscience
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004221000298

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http://www.sciencedirect.com/science/article/pii/S2589004221000298

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