Mesenchymal-Epithelial Interactome Analysis Reveals Essential Factors Required for Fibroblast-Free Alveolosphere Formation

Summary: Lung epithelial cells and fibroblasts are key cell populations in lung development. Fibroblasts support type 2 alveolar epithelial cells (AEC2) in the developing and mature lung. However, fibroblast-AEC2 interactions have not been clearly described. We addressed this in the present study by...

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Bibliographic Details
Main Authors: Kazushige Shiraishi, Shigeyuki Shichino, Satoshi Ueha, Takuya Nakajima, Shinichi Hashimoto, Satoshi Yamazaki, Kouji Matsushima
Format: Article
Language:English
Published: Elsevier 2019-01-01
Series:iScience
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004218302529