PD‐L1 on large extracellular vesicles is a predictive biomarker for therapy response in tissue PD‐L1‐low and ‐negative patients with non‐small cell lung cancer

PD‐L1 on large extracellular vesicles is a predictive biomarker for therapy response in tissue PD‐L1‐low and ‐negative patients with non‐small cell lung cancer

Abstract Immunotherapy has revolutionized the treatment of patients with non‐small cell lung cancer (NSCLC). High expression of tissue PD‐L1 (tPD‐L1) is currently the only approved biomarker for predicting treatment response. However, even tPD‐L1 low (1‐49%) and absent (<1%) patients might benefi...

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Bibliographic Details
Main Authors: Nadja Schöne, Marcel Kemper, Kerstin Menck, Georg Evers, Carolin Krekeler, Arik Bernard Schulze, Georg Lenz, Eva Wardelmann, Claudia Binder, Annalen Bleckmann
Format: Article
Language:English
Published: Wiley 2024-03-01
Series:Journal of Extracellular Vesicles
Subjects:
biomarker
extracellular vesicles
immunotherapy
lung cancer
PD‐L1
Online Access:https://doi.org/10.1002/jev2.12418

Internet

https://doi.org/10.1002/jev2.12418

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