GM-1111 reduces radiation-induced oral mucositis in mice by targeting pattern recognition receptor-mediated inflammatory signaling.

GM-1111 reduces radiation-induced oral mucositis in mice by targeting pattern recognition receptor-mediated inflammatory signaling.

<h4>Purpose</h4>Oral mucositis (OM) is a common, painful side effect of radiation therapy used for the treatment of head and neck cancer (HNC). Activation of the innate immune system upon irradiation has been identified as a key precipitating event of OM. To better understand OM's p...

Full description

Bibliographic Details
Main Authors: Abigail Pulsipher, Justin R Savage, Thomas P Kennedy, Kavita Gupta, Benjamin G Cuiffo, Stephen T Sonis, Won Yong Lee
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0249343

Internet

https://doi.org/10.1371/journal.pone.0249343

Similar Items