Age Impairs Soluble Guanylyl Cyclase Function in Mouse Mesenteric Arteries

Age Impairs Soluble Guanylyl Cyclase Function in Mouse Mesenteric Arteries

Endothelial dysfunction (ED) comes with age, even without overt vessel damage such as that which occurs in atherosclerosis and diabetic vasculopathy. We hypothesized that aging would affect the downstream signalling of the endothelial nitric oxide (NO) system in the vascular smooth muscle (VSM). Wit...

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Bibliographic Details
Main Authors: Cheng Zhong, Minze Xu, Sengül Boral, Holger Summer, Falk-Bach Lichtenberger, Cem Erdoğan, Maik Gollasch, Stefan Golz, Pontus B. Persson, Johanna Schleifenbaum, Andreas Patzak, Pratik H. Khedkar
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:International Journal of Molecular Sciences
Subjects:
aging
mesenteric artery
nitric oxide
soluble guanylyl cyclase
soluble guanylyl cyclase activator
Online Access:https://www.mdpi.com/1422-0067/22/21/11412

Internet

https://www.mdpi.com/1422-0067/22/21/11412

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