High heritability of metabolomic profiles in families burdened with premature cardiovascular disease

High heritability of metabolomic profiles in families burdened with premature cardiovascular disease

Abstract Integration of genetic and metabolic profiling holds promise for providing insight into human disease. Coronary artery disease (CAD) is strongly heritable, but the heritability of metabolomic profiles has not been evaluated in humans. We performed quantitative mass spectrometry‐based metabo...

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Bibliographic Details
Main Authors: Svati H Shah, Elizabeth R Hauser, James R Bain, Michael J Muehlbauer, Carol Haynes, Robert D Stevens, Brett R Wenner, Z Elaine Dowdy, Christopher B Granger, Geoffrey S Ginsburg, Christopher B Newgard, William E Kraus
Format: Article
Language:English
Published: Springer Nature 2009-04-01
Series:Molecular Systems Biology
Subjects:
acylcarnitines
amino acids
heritability
cardiovascular disease
metabolomics
Online Access:https://doi.org/10.1038/msb.2009.11

Internet

https://doi.org/10.1038/msb.2009.11

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