Addiction of mesenchymal phenotypes on the FGF/FGFR axis in oral squamous cell carcinoma cells.

The epithelial-mesenchymal transition (EMT) is a crucial morphological event that occurs during epithelial tumor progression. ZEB1/2 are EMT transcription factors that are positively correlated with EMT phenotypes and breast cancer aggressiveness. ZEB1/2 regulate the alternative splicing and hence i...

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Bibliographic Details
Main Authors: Asami Hotta Osada, Kaori Endo, Yujiro Kimura, Kei Sakamoto, Ryosuke Nakamura, Kaname Sakamoto, Koichiro Ueki, Kunio Yoshizawa, Keiji Miyazawa, Masao Saitoh
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0217451