Anthracycline-induced cardiotoxicity: targeting high-density lipoproteins to limit the damage?

Abstract Doxorubicin (DOX) is an anthracycline antibiotic frequently used against a wide range of cancers, including breast cancer. Although the drug is effective as a treatment against cancer, many patients develop heart failure (HF) months to years following their last treatment with DOX. The chal...

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Bibliographic Details
Main Authors: Carmelita Abrahams, Nicholas J. Woudberg, Sandrine Lecour
Format: Article
Language:English
Published: BMC 2022-09-01
Series:Lipids in Health and Disease
Subjects:
Online Access:https://doi.org/10.1186/s12944-022-01694-y