Replication landscape of the human genome

The physical origin and termination sites of DNA replication in human cells have remained elusive. Here the authors use Okazaki fragment sequencing to reveal global replication patterns and show how chromatin and transcription modulate the process.

Bibliographic Details
Main Authors: Nataliya Petryk, Malik Kahli, Yves d'Aubenton-Carafa, Yan Jaszczyszyn, Yimin Shen, Maud Silvain, Claude Thermes, Chun-Long Chen, Olivier Hyrien
Format: Article
Language:English
Published: Nature Portfolio 2016-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms10208