Mesenchymal gene expression subtyping analysis for early-stage human papillomavirus-negative head and neck squamous cell carcinoma reveals prognostic and predictive applications

Mesenchymal gene expression subtyping analysis for early-stage human papillomavirus-negative head and neck squamous cell carcinoma reveals prognostic and predictive applications

Patients with oral cavity squamous cell carcinoma (OCSCC) are predominantly human papillomavirus (HPV)(−), and treatment typically involves surgical resection ± neck dissection, followed by radiation ± chemotherapy. We previously described four mRNA expression patterns (classical, atypical, basal, a...

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Bibliographic Details
Main Authors: Gregory M. Mayhew, Joshua M. Uronis, David Neil Hayes, Jose P. Zevallos
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Oncology
Subjects:
head and neck
oral cavity
HPV-negative
mesenchymal
gene expression
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.954037/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2022.954037/full

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