Genetic profiling of human bone marrow mesenchymal stromal cells after in vitro expansion in clinical grade human platelet lysate

Genetic profiling of human bone marrow mesenchymal stromal cells after in vitro expansion in clinical grade human platelet lysate

Mesenchymal stromal cells (MSCs) are non-hematopoietic cells that have a broad therapeutic potential. To obtain sufficient cells for clinical application, they must be expanded ex vivo. In the initial expansion protocols described, fetal calf serum (FCS) was used as the reference growth supplement,...

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Bibliographic Details
Main Authors: Ann De Becker, Robbe Heestermans, Wouter De Brouwer, Kara Bockstaele, Ken Maes, Ivan Van Riet
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
mesenchymal stromal cell
expansion
platelet lysate
gene expression
transformation
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2022.1008271/full

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https://www.frontiersin.org/articles/10.3389/fbioe.2022.1008271/full

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