Photonic activation of plasminogen induced by low dose UVB.

Activation of plasminogen to its active form plasmin is essential for several key mechanisms, including the dissolution of blood clots. Activation occurs naturally via enzymatic proteolysis. We report that activation can be achieved with 280 nm light. A 2.6 fold increase in proteolytic activity was...

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Bibliographic Details
Main Authors: Manuel Correia, Torben Snabe, Viruthachalam Thiagarajan, Steffen Bjørn Petersen, Sara R R Campos, António M Baptista, Maria Teresa Neves-Petersen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4312030?pdf=render