Effect of high-dose intravenous ascorbic acid on microcirculation and endothelial glycocalyx during sepsis and septic shock: a double-blind, randomized, placebo-controlled study
Abstract Previous studies indicate supplemental vitamin C improves microcirculation and reduces glycocalyx shedding in septic animals. Our randomized, double-blind, placebo-controlled trial aimed to investigate whether a high dose of intravenous ascorbic acid (AA) might improve microcirculation and...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2023-09-01
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Series: | BMC Anesthesiology |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12871-023-02265-z |