The adjuvant effect of polymuramil, a NOD1 and NOD2 agonist, differs when immunizing mice of different inbred lines with nonstructural hepatitis C virus (Flaviviridae: <i>Hepacivirus</i>)proteins and is synergistically enhanced in combination with pyrogenalum, a TLR4 agonist
Introduction. Hepatitis C is a liver disease with high chronicity, the cause of cirrhosis and hepatocarcinoma. The main obstacle to controlling hepatitis C is the lack of vaccines. The aim of the work was to compare the immunogenic activity of nonstructural recombinant proteins NS3, NS4 and NS5B...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Central Research Institute for Epidemiology
2023-09-01
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| Series: | Вопросы вирусологии |
| Subjects: | |
| Online Access: | https://virusjour.crie.ru/jour/article/viewFile/13159/799 |