An extracellular vesicular mutant KRAS‐associated protein complex promotes lung inflammation and tumor growth

An extracellular vesicular mutant KRAS‐associated protein complex promotes lung inflammation and tumor growth

Abstract Extracellular vesicles (EVs) contain more than 100 proteins. Whether there are EVs proteins that act as an ‘organiser’ of protein networks to generate a new or different biological effect from that identified in EV‐producing cells has never been demonstrated. Here, as a proof‐of‐concept, we...

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Bibliographic Details
Main Authors: Mukesh K. Sriwastva, Yun Teng, Jingyao Mu, Fangyi Xu, Anil Kumar, Kumaran Sundaram, Rajiv Kumar Malhotra, Qingbo Xu, Joshua L. Hood, Lifeng Zhang, Jun Yan, Michael L. Merchant, Juw Won Park, Gerald W. Dryden, Nejat K. Egilmez, Huang‐Ge Zhang
Format: Article
Language:English
Published: Wiley 2023-02-01
Series:Journal of Extracellular Vesicles
Subjects:
extracellular vesicles (EV)
fibronectin (Fn1)
inflammation
KRAS
lung tumour
plant lipid liposomes
Online Access:https://doi.org/10.1002/jev2.12307

Internet

https://doi.org/10.1002/jev2.12307

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