The Curious Case of Arenavirus Entry, and Its Inhibition

The Curious Case of Arenavirus Entry, and Its Inhibition

Arenaviruses comprise a diverse family of enveloped negative-strand RNA viruses that are endemic to specific rodent hosts worldwide. Several arenaviruses cause severe hemorrhagic fevers in humans, including Junín and Machupo viruses in South America and Lassa fever virus in western Africa. Arenaviru...

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Bibliographic Details
Main Authors: Joanne York, Jack H. Nunberg
Format: Article
Language:English
Published: MDPI AG 2012-01-01
Series:Viruses
Subjects:
arenavirus
envelope glycoprotein
fusion protein
fusion inhibitor
pH-dependent membrane fusion
endosome
antiviral
zinc binding
stable signal peptide
hemorrhagic fever
Online Access:http://www.mdpi.com/1999-4915/4/1/83/

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http://www.mdpi.com/1999-4915/4/1/83/

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