Systems biology reveals anatabine to be an NRF2 activator

Systems biology reveals anatabine to be an NRF2 activator

Anatabine, an alkaloid present in plants of the Solanaceae family (including tobacco and eggplant), has been shown to ameliorate chronic inflammatory conditions in mouse models, such as Alzheimer’s disease, Hashimoto’s thyroiditis, multiple sclerosis, and intestinal inflammation. However, the mechan...

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Bibliographic Details
Main Authors: Dimitris E. Messinis, Carine Poussin, Diogo A. R. S. Latino, Yvan Eb-Levadoux, Remi Dulize, Dariusz Peric, Emmanuel Guedj, Bjoern Titz, Nikolai V. Ivanov, Manuel C. Peitsch, Julia Hoeng
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Pharmacology
Subjects:
anatabine
Nrf2 activator
Nrf2 activation
Nrf2 pathway
Nrf2
HMOX1
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.1011184/full

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https://www.frontiersin.org/articles/10.3389/fphar.2022.1011184/full

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