Effect of Voacamine upon inhibition of hypoxia induced fatty acid synthesis in a rat model of methyln-nitrosourea induced mammary gland carcinoma

Abstract Background In the present study, fatty acid synthesis is targeted to combat mammary gland carcinoma by activating prolyl hydroxylase-2 with Voacamine alone and in combination with Tamoxifen. It was hypothesized that the activation of prolyl hydroxylase-2 would inhibit the hypoxia-induced fa...

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Bibliographic Details
Main Authors: Lakhveer Singh, Manjari Singh, Shubham Rastogi, Anurag Choudhary, Dinesh Kumar, Ritu Raj, Mohd Nazam Ansari, Abdulaziz S. Saeedan, Gaurav Kaithwas
Format: Article
Language:English
Published: BMC 2021-06-01
Series:BMC Molecular and Cell Biology
Subjects:
Online Access:https://doi.org/10.1186/s12860-021-00371-9