Therapeutic vaccines against human and rat renin in spontaneously hypertensive rats.

Vaccination provides a promising approach for treatment of hypertension and improvement in compliance. As the initiation factor of renin-angiotensin system, renin plays a critical role in hypertension. In this study, we selected six peptides (rR32, rR72, rR215, hR32, hR72, and hR215) belonging to po...

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Bibliographic Details
Main Authors: Zhihua Qiu, Xiao Chen, Yanzhao Zhou, Jibin Lin, Dan Ding, Shijun Yang, Fen Chen, Min Wang, Feng Zhu, Xian Yu, Zihua Zhou, Yuhua Liao
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3692469?pdf=render