Microglia Gravitate toward Amyloid Plaques Surrounded by Externalized Phosphatidylserine via TREM2

Microglia Gravitate toward Amyloid Plaques Surrounded by Externalized Phosphatidylserine via TREM2

Abstract Microglia play a crucial role in synaptic elimination by engulfing dystrophic neurons via triggering receptors expressed on myeloid cells 2 (TREM2). They are also involved in the clearance of beta‐amyloid (Aβ) plaques in Alzheimer's disease (AD); nonetheless, the driving force behind T...

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Bibliographic Details
Main Authors: Jong‐Chan Park, Jong Won Han, Woochan Lee, Jieun Kim, Sang‐Eun Lee, Dongjoon Lee, Hayoung Choi, Jihui Han, You Jung Kang, Yen N. Diep, Hansang Cho, Rian Kang, Won Jong Yu, Jean Lee, Murim Choi, Sun‐Wha Im, Jong‐Il Kim, Inhee Mook‐Jung
Format: Article
Language:English
Published: Wiley 2024-09-01
Series:Advanced Science
Subjects:
Alzheimer's disease
beta‐amyloid
microglia
phosphatidylserine
TREM2
Online Access:https://doi.org/10.1002/advs.202400064

Internet

https://doi.org/10.1002/advs.202400064

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