Reversion of MRAP2 Protein Sequence Generates a Functional Novel Pharmacological Modulator for MC4R Signaling

As a member of the melanocortin receptor family, melanocortin 4 receptor (MC4R) plays a critical role in regulating energy homeostasis and feeding behavior, and has been proven as a promising therapeutic target for treating severe obesity syndrome. Numerous studies have demonstrated that central MC4...

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Bibliographic Details
Main Authors: Jing Xu, Meng Wang, Yanbin Fu, Cong Zhang, Zhe Kuang, Shan Bian, Rui Wan, Shen Qu, Chao Zhang
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Biology
Subjects:
Online Access:https://www.mdpi.com/2079-7737/11/6/874