Structure of the Intermediate Filament-Binding Region of Desmoplakin.

Desmoplakin (DP) is a cytoskeletal linker protein that connects the desmosomal cadherin/plakoglobin/plakophilin complex to intermediate filaments (IFs). The C-terminal region of DP (DPCT) mediates IF binding, and contains three plakin repeat domains (PRDs), termed PRD-A, PRD-B and PRD-C. Previous cr...

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Bibliographic Details
Main Authors: Hyunook Kang, Thomas M Weiss, Injin Bang, William I Weis, Hee-Jung Choi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4726743?pdf=render