The Citrullination-Neutrophil Extracellular Trap Axis in Chronic Diseases

Citrullination of proteins is crucial for the formation of neutrophil extracellular traps (NETs) – strands of nuclear DNA expulsed in the extracellular environment along with antimicrobial proteins in order to halt the spread of pathogens. Paradoxically, NETs may be immunogenic and contribute to inf...

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Bibliographic Details
Main Authors: Martin Maronek, Roman Gardlik
Format: Article
Language:English
Published: Karger Publishers 2022-03-01
Series:Journal of Innate Immunity
Subjects:
Online Access:https://www.karger.com/Article/FullText/522331