The Citrullination-Neutrophil Extracellular Trap Axis in Chronic Diseases
Citrullination of proteins is crucial for the formation of neutrophil extracellular traps (NETs) – strands of nuclear DNA expulsed in the extracellular environment along with antimicrobial proteins in order to halt the spread of pathogens. Paradoxically, NETs may be immunogenic and contribute to inf...
Main Authors: | , |
---|---|
Format: | Article |
Language: | English |
Published: |
Karger Publishers
2022-03-01
|
Series: | Journal of Innate Immunity |
Subjects: | |
Online Access: | https://www.karger.com/Article/FullText/522331 |