CXCR4-enriched T regulatory cells preferentially home to bone marrow and resolve inflammation

CXCR4-enriched T regulatory cells preferentially home to bone marrow and resolve inflammation

Summary: CXCR4 cell surface expression is critical for the homing of T regulatory (Treg) cells to the bone marrow (BM). We hypothesize that CXCR4 enrichment on Tregs cell surface may abbreviate their transit time to reach BM. Umbilical cord-blood CD25+ Tregs underwent CXCR4 dual enrichment and ex vi...

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Bibliographic Details
Main Authors: Meixian Huang, Zeng Ke, Mi-Ae Lyu, Lucia Masarova, Tara Sadeghi, Christopher R. Flowers, Simrit Parmar
Format: Article
Language:English
Published: Elsevier 2024-09-01
Series:iScience
Subjects:
Immunology
Immunity
Cell biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004224020558

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http://www.sciencedirect.com/science/article/pii/S2589004224020558

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