IL-1beta processing in host defense: beyond the inflammasomes.

IL-1beta processing in host defense: beyond the inflammasomes.

Stimulation and release of proinflammatory cytokines is an essential step for the activation of an effective innate host defense, and subsequently for the modulation of adaptive immune responses. Interleukin-1beta (IL-1beta) and IL-18 are important proinflammatory cytokines that on the one hand acti...

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Bibliographic Details
Main Authors: Mihai G Netea, Anna Simon, Frank van de Veerdonk, Bart-Jan Kullberg, Jos W M Van der Meer, Leo A B Joosten
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-02-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC2829053?pdf=render

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