Absence of clustering of phosphatidylinositol-(4,5)-bisphosphate in fluid phosphatidylcholine

Phosphatidylinositol-(4,5)-bisphosphate [PI(4,5)P2] plays a key role in the modulation of actin polymerization and vesicle trafficking. These processes seem to depend on the enrichment of PI(4,5)P2 in plasma membrane domains. Here, we show that PI(4,5)P2 does not form domains when in a fluid phospha...

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Bibliographic Details
Main Authors: Faébio Fernandes, Luiés M.S. Loura, Alexander Fedorov, Manuel Prieto
Format: Article
Language:English
Published: Elsevier 2006-07-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520331965