Cardiac alterations in human African trypanosomiasis (T.b. gambiense) with respect to the disease stage and antiparasitic treatment.

In Human African Trypanosomiasis, neurological symptoms dominate and cardiac involvement has been suggested. Because of increasing resistance to the available drugs for HAT, new compounds are desperately needed. Evaluation of cardiotoxicity is one parameter of drug safety, but without knowledge of t...

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Bibliographic Details
Main Authors: Johannes A Blum, Caecilia Schmid, Christian Burri, Christoph Hatz, Carol Olson, Blaise Fungula, Leon Kazumba, Patrick Mangoni, Florent Mbo, Kambau Deo, Alain Mpanya, Amadeo Dala, Jose R Franco, Gabriele Pohlig, Michael J Zellweger
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC2640099?pdf=render