Evaluation of GammaH2AX in Buccal Cells as a Molecular Biomarker of DNA Damage in Alzheimer’s Disease in the AIBL Study of Ageing
In response to double-stranded breaks (DSBs) in chromosomal DNA, H2AX (a member of histone H2A family) becomes phosphorylated to form γH2AX. Although increased levels of γH2AX have been reported in the neuronal nuclei of Alzheimer’s disease (AD) patients, the understanding of γH2AX responses in bucc...
| Главные авторы: | , , , , , , , , , |
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| Формат: | Статья |
| Язык: | English |
| Опубликовано: |
MDPI AG
2020-08-01
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| Серии: | Life |
| Предметы: | |
| Online-ссылка: | https://www.mdpi.com/2075-1729/10/8/141 |