Platelet accumulation in an endothelium-coated elastic vein valve model of deep vein thrombosis is mediated by GPIbα—VWF interaction

Platelet accumulation in an endothelium-coated elastic vein valve model of deep vein thrombosis is mediated by GPIbα—VWF interaction

Deep vein thrombosis is a life-threatening disease that takes millions of people's lives worldwide. Given both technical and ethical issues of using animals in research, it is necessary to develop an appropriate in vitro model that would recapitulate the conditions of venous thrombus developmen...

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Bibliographic Details
Main Authors: Hosam Alden Baksamawi, Alessio Alexiadis, Daniele Vigolo, Alexander Brill
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-04-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
DVT
microfluidics
platelets
von Willebrand factor
glycoprotein Ibα
hydrodynamics
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2023.1167884/full

Internet

https://www.frontiersin.org/articles/10.3389/fcvm.2023.1167884/full

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