The stem cell population of the human colon crypt: analysis via methylation patterns.

The analysis of methylation patterns is a promising approach to investigate the genealogy of cell populations in an organism. In a stem cell-niche scenario, sampled methylation patterns are the stochastic outcome of a complex interplay between niche structural features such as the number of stem cel...

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Bibliographic Details
Main Authors: Pierre Nicolas, Kyoung-Mee Kim, Darryl Shibata, Simon Tavaré
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-03-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC1808490?pdf=render