The stem cell population of the human colon crypt: analysis via methylation patterns.
The analysis of methylation patterns is a promising approach to investigate the genealogy of cell populations in an organism. In a stem cell-niche scenario, sampled methylation patterns are the stochastic outcome of a complex interplay between niche structural features such as the number of stem cel...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2007-03-01
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Series: | PLoS Computational Biology |
Online Access: | http://europepmc.org/articles/PMC1808490?pdf=render |