Role of Human Antigen R (HuR) in the Regulation of Pulmonary ACE2 Expression

Role of Human Antigen R (HuR) in the Regulation of Pulmonary ACE2 Expression

Patients with COPD may be at an increased risk for severe illness from COVID-19 because of ACE2 upregulation, the entry receptor for SARS-CoV-2. Chronic exposure to cigarette smoke, the main risk factor for COPD, increases pulmonary ACE2. How ACE2 expression is controlled is not known but may involv...

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Bibliographic Details
Main Authors: Noof Aloufi, Zahraa Haidar, Jun Ding, Parameswaran Nair, Andrea Benedetti, David H. Eidelman, Imed-Eddine Gallouzi, Sergio Di Marco, Sabah N. Hussain, Carolyn J. Baglole
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Cells
Subjects:
HuR
ACE2
fibroblast
COVID-19
chronic obstructive pulmonary disease
<i>ELAVL1</i>
Online Access:https://www.mdpi.com/2073-4409/11/1/22

Internet

https://www.mdpi.com/2073-4409/11/1/22

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