Adjuvant effect of dispersed fullerene C60 on the immune response to constructs harboring amino acid and nucleotide sequences of hepatitis C virus nonstructural NS5B protein

Adjuvant effect of dispersed fullerene C60 on the immune response to constructs harboring amino acid and nucleotide sequences of hepatitis C virus nonstructural NS5B protein

Introduction. A vaccine against hepatitis C has not yet been developed. Recombinant proteins and plasmids encoding hepatitis C virus (HCV) proteins, the components of candidate vaccines, induce a weak immune response and require the use of adjuvants. The aim of the work was to study the adjuvant...

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Main Authors: Olga V. Masalova, Ekaterina I. Lesnova, Sergey M. Andreev, Nadezhda N. Shershakova, Vyacheslav V. Kozlov, Kristina Yu. Permyakova, Natalia A. Demidova, Vladimir T. Valuev-Elliston, Evgeny A. Turetskiy, Alexander V. Ivanov, Tatyana N. Nikolaeva, Musa R. Khaitov, Alexander V. Pronin, Alla A. Kushch
Format: Article
Language:English
Published: Central Research Institute for Epidemiology 2023-02-01
Series:Вопросы вирусологии
Subjects:
hepatitis c virus
nonstructural ns5b protein
dna immunization
fullerene c60
adjuvants
immune response
Online Access:https://virusjour.crie.ru/jour/article/viewFile/665/429

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https://virusjour.crie.ru/jour/article/viewFile/665/429

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