A mitochondria-targeting dihydroartemisinin derivative as a reactive oxygen species -based immunogenic cell death inducer

Summary: Immunogenic cell death (ICD) can activate the anticancer immune response and its occurrence requires high reliance on oxidative stress. Inducing mitochondrial reactive oxygen species (ROS) is a desirable capability for ICD inducers. However, in the category of ICD-associated drugs, numerous...

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Bibliographic Details
Main Authors: Hong-Yang Zhao, Kun-Heng Li, Dan-Dan Wang, Zhi-Li Zhang, Zi-Jian Xu, Ming-Hui Qi, Shi-Wen Huang
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223027797