<i>PAX5</i> Alterations in a Consecutive Childhood B-Cell Acute Lymphoblastic Leukemia Cohort Treated Using the ALL IC-BFM 2009 Protocol

<i>PAX5</i> Alterations in a Consecutive Childhood B-Cell Acute Lymphoblastic Leukemia Cohort Treated Using the ALL IC-BFM 2009 Protocol

In this study, we aimed to identify patients within our B-ALL cohort with altered <i>PAX5</i>. Our objective was to use a comprehensive analysis approach to characterize the types of genetic changes, determine their origin (somatic/germline), and analyze the clinical outcomes associated...

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Bibliographic Details
Main Authors: Klementina Črepinšek, Nika Klobučar, Tine Tesovnik, Robert Šket, Barbara Jenko Bizjan, Jernej Kovač, Marko Kavčič, Tomaž Prelog, Lidija Kitanovski, Janez Jazbec, Maruša Debeljak
Format: Article
Language:English
Published: MDPI AG 2024-03-01
Series:Cancers
Subjects:
childhood B-cell acute lymphoblastic leukemia
<i>PAX5</i> genetic alterations
prognostic significance
Online Access:https://www.mdpi.com/2072-6694/16/6/1164

Internet

https://www.mdpi.com/2072-6694/16/6/1164

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