From early lessons to new frontiers: The worm as a treasure trove of small RNA biology

In the past twenty years, the tiny soil nematode C. elegans has provided critical insights into our understanding of the breadth of small RNA-mediated gene regulatory activities. The first microRNA was identified in C. elegans in 1993, and the understanding that dsRNA was the driving force behind RN...

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Bibliographic Details
Main Authors: Elaine M. Youngman, Julie M Claycomb
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-11-01
Series:Frontiers in Genetics
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2014.00416/full