Memantine prevents cardiomyocytes nuclear size reduction in the left ventricle of rats exposed to cold stress

Memantine prevents cardiomyocytes nuclear size reduction in the left ventricle of rats exposed to cold stress

OBJECTIVES: Memantine is an N-methyl-d-aspartate (NMDA) glutamate receptor antagonist used to treat Alzheimer's disease. Previous studies have suggested that receptor blockers act as neuroprotective agents; however, no study has specifically investigated the impact that these drugs have on the...

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Bibliographic Details
Main Authors: Adriano Meneghini, Celso Ferreira, Luiz Carlos de Abreu, Vitor E. Valenti, Marcelo Ferreira, Celso F. Filho, Neif Murad
Format: Article
Language:English
Published: Elsevier España 2009-01-01
Series:Clinics
Subjects:
Memantine
Cardiac myocytes
Cardiotonic agents
Cell nucleus structures
Heart
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322009000900014

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322009000900014

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