Design and synthesis of a potential selective JAK-3 inhibitor for the treatment of rheumatoid arthritis using predictive QSAR models
Rheumatoid arthritis is a chronic autoimmune illness characterized by joint dysfunction. New drugs are available, among them Janus Kinase enzyme inhibitor drugs, whose significant side effects are associated with neutropenia, thrombocytopenia, and dyslipidemia due to nonselective inhibition of this...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2024-01-01
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| Series: | Informatics in Medicine Unlocked |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2352914824000200 |