Identification of a Novel TECTA mutation in a Chinese DFNA8/12 family with prelingual progressive sensorineural hearing impairment.

Identification of a Novel TECTA mutation in a Chinese DFNA8/12 family with prelingual progressive sensorineural hearing impairment.

Tectorial membrane, an extracellular matrix of the cochlea, plays a crucial role in the transmission of sound to the sensory hair cells. Alpha-tectorin is the most important noncollagenous component of the tectorial membrane and the otolith membrane in the maculae of the vestibular system. Defects i...

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Bibliographic Details
Main Authors: Zhengyue Li, Yilian Guo, Yu Lu, Jianzhong Li, Zhanguo Jin, Hongbo Li, Yanping Lu, Pu Dai, Dongyi Han, Jing Cheng, Huijun Yuan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3729559?pdf=render

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http://europepmc.org/articles/PMC3729559?pdf=render

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