Clinical effectiveness and cost-effectiveness of imatinib dose escalation for the treatment of unresectable and/or metastatic gastrointestinal stromal tumours that have progressed on treatment at a dose of 400 mg/day: a systematic review and economic evaluation

Background: Imatinib dose escalation is advocated for gastrointestinal stromal tumour (GIST) treatment, but its effectiveness compared with sunitinib and best supportive care (BSC) after failure at the 400 mg/day dose is unknown. Objectives: To assess the effectiveness and cost-effectiveness of imat...

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Bibliographic Details
Main Authors: J Hislop, Z Quayyum, A Elders, C Fraser, D Jenkinson, G Mowatt, P Sharma, L Vale, R Petty
Format: Article
Language:English
Published: NIHR Journals Library 2011-06-01
Series:Health Technology Assessment
Subjects:
Online Access:https://doi.org/10.3310/hta15250