CRISPR/Cas9 Mutagenesis in <named-content content-type="genus-species">Phlebotomus papatasi</named-content>: the Immune Deficiency Pathway Impacts Vector Competence for <named-content content-type="genus-species">Leishmania major</named-content>

ABSTRACT Sand flies are the natural vectors for the Leishmania species that produce a spectrum of diseases in their mammalian hosts, including humans. Studies of sand fly/Leishmania interactions have been limited by the absence of genome editing techniques applicable to these insects. In this report...

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Bibliographic Details
Main Authors: Isabelle Louradour, Kashinath Ghosh, Ehud Inbar, David L. Sacks
Format: Article
Language:English
Published: American Society for Microbiology 2019-08-01
Series:mBio
Subjects:
Online Access:https://journals.asm.org/doi/10.1128/mBio.01941-19