Neurodegeneration in Alzheimer's disease: caspases and synaptic element interdependence
<p>Abstract</p> <p>Extensive genetic, biochemical, and histological evidence has implicated the amyloid-β peptide (Aβ) in Alzheimer's disease pathogenesis, and several mechanisms have been suggested, such as metal binding, reactive oxygen species production, and membrane pore...
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Format: | Article |
Language: | English |
Published: |
BMC
2009-06-01
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Series: | Molecular Neurodegeneration |
Online Access: | http://www.molecularneurodegeneration.com/content/4/1/27 |