Presence of anti-Glomerular basement membrane (GBM) antibodies and Myeloperoxidase anti neutrophilic cytoplasmic antibodies (MPO ANCA) in a case of rapidly progressive glomerulonephritis.

Presence of anti-Glomerular basement membrane (GBM) antibodies and Myeloperoxidase anti neutrophilic cytoplasmic antibodies (MPO ANCA) in a case of rapidly progressive glomerulonephritis.

A 69 year old male developed rapid deterioration of kidney function and developed uremic symptoms. Creatinine was 486.2 µmol/L (5.5 mg/dl) on presentation. Anti-MPO was positive (titer>8 units, normal <0.4). He was clinically diagnosed with rapidly proliferative glomerulonephritis (RPGN) most...

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Bibliographic Details
Main Authors: Gaurang P Mavani, Max ePommier, Sandar eWin, Michael Frank Michelis, Jordan eRosenstock
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-08-01
Series:Frontiers in Medicine
Subjects:
Cyclophosphamide
Plasmapheresis
RPGN
Anti -MPO antibody
Anti- GBM antibody
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmed.2015.00053/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fmed.2015.00053/full

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