Minimized Extracorporeal Circulation Is Associated with Reduced Plasma Levels of Free-Circulating Mitochondrial DNA Compared to Conventional Cardiopulmonary Bypass: A Secondary Analysis of an Exploratory, Prospective, Interventional Study

Minimized Extracorporeal Circulation Is Associated with Reduced Plasma Levels of Free-Circulating Mitochondrial DNA Compared to Conventional Cardiopulmonary Bypass: A Secondary Analysis of an Exploratory, Prospective, Interventional Study

The use of minimized extracorporeal circulation (MiECC) during cardiac surgery is associated with a reduced inflammatory reaction compared to conventional cardiopulmonary bypass (cCPB). Since it is unknown if MiECC also reduces the amount of free-circulating mitochondrial DNA (mtDNA), this study aim...

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Bibliographic Details
Main Authors: Thomas Zajonz, Christian Koch, Jan Schwiddessen, Melanie Markmann, Matthias Hecker, Fabian Edinger, Götz Schmidt, Andreas Boening, Michael Sander, Emmanuel Schneck
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Journal of Clinical Medicine
Subjects:
cardiac surgery
DAMPs
SIRS
inflammation
coronary artery bypass graft
Online Access:https://www.mdpi.com/2077-0383/11/11/2994

Internet

https://www.mdpi.com/2077-0383/11/11/2994

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