Structure of the gene therapy vector, adeno-associated virus with its cell receptor, AAVR

Structure of the gene therapy vector, adeno-associated virus with its cell receptor, AAVR

Adeno-associated virus (AAV) vectors are preeminent in emerging clinical gene therapies. Generalizing beyond the most tractable genetic diseases will require modulation of cell specificity and immune neutralization. Interactions of AAV with its cellular receptor, AAVR, are key to understanding cell-...

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Bibliographic Details
Main Authors: Nancy L Meyer, Guiqing Hu, Omar Davulcu, Qing Xie, Alex J Noble, Craig Yoshioka, Drew S Gingerich, Andrew Trzynka, Larry David, Scott M Stagg, Michael Stewart Chapman
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2019-05-01
Series:eLife
Subjects:
electron microscopy
viral vector
human
atomic
entry
trafficking
Online Access:https://elifesciences.org/articles/44707

Internet

https://elifesciences.org/articles/44707

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