Soluble ST2 in Heart Failure: A Clinical Role beyond B-Type Natriuretic Peptide

Soluble (s)ST2 has been proposed as a useful biomarker for heart failure (HF) patient management. Myocardial damage or mechanical stress stimulate sST2 release. ST2 competes with a membrane bound receptor (ST2 ligand, or ST2L) for interleukin-33 (IL-33) binding, inhibiting the effects induced by the...

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Bibliographic Details
Main Authors: Mauro Riccardi, Peder L. Myhre, Thomas A. Zelniker, Marco Metra, James L. Januzzi, Riccardo M. Inciardi
Format: Article
Language:English
Published: MDPI AG 2023-11-01
Series:Journal of Cardiovascular Development and Disease
Subjects:
Online Access:https://www.mdpi.com/2308-3425/10/11/468